PMID 40280987

Research
All papers

Maintenance of time-restricted eating and high-intensity interval training in women with overweight/obesity 2 years after a randomized controlled trial

Question

Do women with overweight or obesity maintain TRE and/or HIIT 2 years after a supervised 7-week randomized trial, and are cardiometabolic outcomes maintained?

Summary

This 2-year follow-up of the TREHIIT randomized trial asked whether women with overweight or obesity continued time-restricted eating or HIIT after a 7-week supervised intervention. About one-third of the original HIIT group and 45% of the combined TREHIIT group still reported doing HIIT after 2 years, but cardiometabolic between-group differences were not statistically significant at the stricter threshold. Participants described HIIT as time-efficient and mastery-building, while lack of time, pain, injury, motivation, and exertion discomfort were common barriers.

Methodology

  • Women with overweight or obesity from the TREHIIT trial.
  • 59 participants.
  • Treadmill running or stationary cycling.
  • Work intervals: 4 min and 1 min intervals.
  • Recovery: 3 min active recovery or 1 min low-intensity standing/walking.
  • Intensity: 90-95% HRmax or maximum sustainable 1-min intensity.
  • 3 sessions/week.
  • 7 weeks.
  • Two-year follow-up of a randomized controlled trial, analyzed by original group assignment.
  • HIIT continuation, Body composition, VO2peak, and Cardiometabolic blood markers were tracked.

Outcomes

HIIT maintenance

4/12 original HIIT participants and 9/20 TREHIIT participants still reported undertaking HIIT after 2 years.

HIIT 33%; TREHIIT 45%.

Mixed

Cardiometabolic between-group outcomes

No statistically significant between-group differences at p<0.01 after 2 years.

Non-significant body mass HIIT vs CON p=0.019 and visceral fat TREHIIT vs CON p=0.015.

No clear change

Within-group body composition and fitness

HIIT and TREHIIT had lower body mass, fat mass, and visceral fat area and higher VO2peak versus baseline at 2 years.

HIIT fat mass -4.2 kg p<0.001; visceral fat -19 cm2 p<0.001; VO2peak +2.7 mL/kg/min p=0.002.

Improved

Experience and barriers

HIIT was rated favorably and valued for time-efficiency/mastery, but lack of time, injury, pain, motivation, difficulty, and exertion discomfort were barriers.

HIIT rating 7.5 (2.1)/10.

Mixed

Insights

  • A short supervised HIIT block may seed longer-term exercise habits for some users.
  • Long-term adherence support should address time, injury/pain, motivation, and exertion discomfort.
  • Adding exercise variety may help people who enjoy HIIT but do not want only HIIT.

Limitations

  • Only a subset attended 2-year follow-up
  • Self-selection bias
  • Recall bias from self-reported continuation
  • No objective adherence or interim physical activity data
  • Limited power and multiple comparisons

Safety

  • Injury and pain were reported as barriers to maintaining HIIT.
  • No formal adverse-event count was reported in this follow-up article.