PMID 39852308

Research
All papers

Interindividual Variability Response to Resistance and High-Intensity Interval Training on Blood Pressure Reduction in Hypertensive Older Adults

Question

How do low-volume resistance training and HIIT affect systolic and diastolic blood pressure, responder status, and blood-pressure category distribution in hypertensive older adults?

Summary

This randomized trial compared low-volume resistance training, low-volume cycling HIIT, and usual pharmacological care in physically inactive older adults with hypertension. HIIT used 30-minute sessions, three times per week for 8 weeks, with 8-10 one-minute hard cycling intervals and two-minute active rests. Both resistance training and HIIT lowered systolic blood pressure, but not diastolic blood pressure, and both reduced the proportion of non-responders over time. HIIT also shifted some participants from worse blood-pressure categories toward normal or lower-risk categories.

Methodology

  • Physically inactive hypertensive older adults with BMI 25-39.9 kg/m2 and pharmacological treatment.
  • 39 participants.
  • Cycle ergometer.
  • Work intervals: 1 minute at modified Borg 8-10.
  • Recovery: 2 minutes active rest.
  • Intensity: Borg 8-10, progressed by resistance if below Borg 8.
  • 30 minutes average including warm-up and cool-down.
  • 3 sessions per week.
  • 8 weeks.
  • Randomized clinical trial with resistance training, HIIT, and control groups.
  • Systolic blood pressure, Diastolic blood pressure, Responder status, and Blood-pressure category distribution were tracked.

Outcomes

Systolic blood pressure

HIIT and RT significantly improved SBP by week 8, with average reductions around 12-13 mmHg discussed by authors.

HIIT week 8 p = 0.0005, d = 0.8; RT week 8 p = 0.015, d = 1.12; time effect F = 7.562, p = 0.001.

Improved

Diastolic blood pressure

DBP did not significantly change by group, time, or group-by-time interaction.

Group F = 0.722, p = 0.493; time F = 1.803, p = 0.172; group x time F = 0.108, p = 0.979.

No clear change

Non-responder prevalence

Non-responder prevalence decreased in HIIT for SBP from 69% at week 4 to 46% at week 8 and for DBP from 69% to 38%.

Reported in Table 3 narrative.

Improved

Blood-pressure category

In HIIT, normal BP increased from 8% to 23%, HTN stage 1 decreased from 38% to 23%, and HTN stage 2 decreased from 46% to 23%.

Reported in Table 4 narrative.

Improved

Insights

  • For hypertensive older adults, HIIT can use RPE-based one-minute cycling intervals rather than all-out sprints.
  • Eight weeks may reduce apparent non-response compared with four weeks.
  • Blood-pressure benefits may be systolic-specific; do not promise DBP reductions from this study.
  • Medication-managed users require BP monitoring as exercise lowers pressure.

Limitations

  • Small clinical sample.
  • Convenience recruitment.
  • Medication co-treatment complicates attribution.
  • Actual adverse events and exact attrition were not clearly extracted from visible text.
  • Requires supervision and monitoring.

Safety

  • HR and BP were measured before and after every session.
  • Sessions were to be suspended if SBP > 180 mmHg or DBP > 110 mmHg.
  • Adverse event counts were not visible in extracted result sections.