# Adherence Patterns and Health Outcomes in Spanish Young Women Participating in a Virtual-Guided HIIT Program: Insights from the Randomized Controlled WISE Trial

PMID: 39408141
Journal: Healthcare (Basel, Switzerland)
Published: 2024 Oct 1
Authors: Ferrando-Terradez I, San Martín Valenzuela C, Dueñas L, Alcántara E, Sendín-Magdalena A, Ezzatvar Y

## Question

Does an unsupervised virtual-guided HIIT program improve adherence, daily steps, self-reported physical activity, sleep quality, and quality of life among young women compared with control?

## Summary

This Spanish center report from the WISE randomized trial tested a 6-month remotely delivered, app-guided HIIT program in young sedentary women. The program had moderate adherence among completers, but daily steps decreased in both intervention and control groups, sleep quality worsened, and quality-of-life scores did not change. Self-reported physical activity shifted upward, but group differences were not significant.

## Population

- Sedentary young women recruited from schools and universities.
- Sample size: 106
- Age: Eligible age 15-24 years; completers in intervention averaged 21.10 years and controls 21.04 years.
- Sex: Young women only.
- Fitness level: Sedentary by non-compliance with WHO physical activity recommendations and IPAQ score <1.
- Health status: Excluded diabetes, cardiac problems incompatible with exercise, unwillingness to wear smartwatch, and severe COVID-19 history.

## Methodology

- Single-blind randomized controlled trial report from the Spanish WISE study center.
- 6 months, with baseline, halfway, and final assessments.
- Remote mobile-app intervention in Valencia, Spain; face-to-face assessments at the University of Valencia Physiotherapy Department.
- Randomized and controlled study design.

## Protocol

- WISE virtual-guided HIIT.
- Modality: Mobile-app exercise videos.
- Sets or repetitions: Video-guided sessions; exact interval structure not reported in this outcomes article.
- Intensity: Gradually increased; two intensity levels offered from session 10; perceived exertion averaged 6.34 on modified Borg scale.
- Session duration: 20-30 minutes including 5-7 minute warm-up, 10-15 minute HIIT, and 5-7 minute cooldown/stretching.
- Frequency: Adherence-duration criterion was at least 20 minutes twice per week; prescribed weekly frequency not clearly stated in this article.
- Program length: 6 months.
- Progression: Exercises increased in intensity over sessions and offered level choice from session 10.
- Control with guidelines and activity monitor.
- Modality: General physical activity guidance and smartwatch access.
- Program length: 6 months.
- Progression: Control received exercise videos and educational messages after study completion.

## Outcomes

### Daily steps
Status: worse/safety concern
Daily steps decreased over time in both intervention and control groups, with no significant group-by-time interaction.

Time effect F(1.61,133.92)=15.43, p<0.01, partial eta squared=0.16; group effect p=0.12.

### Sleep quality
Status: worse/safety concern
PSQI scores worsened at midterm and post-intervention in both groups.

Time effect F(1.84,152.73)=24.65, p<0.01, partial eta squared=0.23; group effect p=0.07.

### Quality of life
Status: no clear change
HLPCQ quality-of-life/lifestyle score did not significantly change.

Time effect p=0.89; group effect p=0.71.

### Self-reported physical activity
Status: mixed
IPAQ categories shifted from low toward moderate/high activity in both groups, but groups did not differ statistically.

Intervention time effect chi-square(2)=46.97, p<0.01; control chi-square(2)=16.28, p<0.01; no group differences at measurement times.

## Practical Insights

- Remote HIIT needs adherence monitoring beyond video access because only about one-third met the twice-weekly 20-minute duration criterion.
- Daily steps may decline even when self-reported activity improves, so apps should monitor total activity compensation.
- Sleep should be monitored when high-intensity programs are delivered remotely.

## Limitations

- Spanish-center analysis rather than full multinational WISE trial.
- External factors such as season, exam periods, holidays, and temperature were not controlled.
- Menstrual cycle was not controlled.
- No long-term post-program follow-up.
- Exact interval structure and physiological intensity targets were not reported in this outcomes article.

## Safety And Adherence

- No explicit adverse-event reporting was found in the extracted text.
- Cardiac problems incompatible with exercise were an exclusion criterion.

## Original Sources

- [PubMed](https://pubmed.ncbi.nlm.nih.gov/39408141/) (pubmed)
- [DOI](https://doi.org/10.3390/healthcare12191961) (doi)
- [PMC full text](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11475678/) (full text)

## Agent Guidance

Preserve the paper-level scope of this note. Do not generalize beyond the population, protocol, measured outcomes, and limitations above.